Terminator Salvation

In 2003, Doctor Serena Kogan (Helena Bonham Carter) of Cyberdyne Systems convinces death row inmate Marcus Wright (Sam Worthington) to sign his body over for medical research following his execution by lethal injection. One year later the Skynet system is activated, perceives humans as a threat to its own existence, and eradicates much of humanity in the event known as "Judgment Day" (as depicted in Terminator 3: Rise of the Machines).
In 2018, John Connor (Christian Bale) leads a Resistance attack on a Skynet base. John discovers human prisoners and schematics for a new type of Terminator incorporating living tissue, but he is the only apparent survivor of the attack after the base is destroyed in a nuclear explosion. However, Marcus emerges from the wreckage of the base and proceeds on foot to Los Angeles.
John returns to Resistance headquarters located aboard a nuclear submarine and tells General Ashdown (Michael Ironside), the current leader, of his discovery. Meanwhile, the Resistance has discovered a radio frequency believed to be capable of sending an order to shut down Skynet machines. They plan to launch an offensive against the Skynet base in San Francisco in four days, in response to an intercepted "kill list" indicating that Skynet plans to kill the Resistance's command staff in a week's time. John learns that his own name is second on the list, following a civilian named Kyle Reese. The Resistance leaders are unaware of Kyle's importance, but John knows that it is because Kyle will later become his father (as depicted in The Terminator). John meets with his wife Kate (Bryce Dallas Howard) and his subordinate Barnes (Common), and transmits a radio broadcast to Resistance members and surviving civilians around the world.
Arriving in the ruins of Los Angeles, Marcus is saved from a T-600 Terminator by Kyle Reese (Anton Yelchin) and his mute child companion Star (Jadagrace Berry). Kyle informs Marcus about the war between humans and Skynet. Hearing John's radio broadcast, the three leave Los Angeles in search of the Resistance. They survive an attack, but Kyle, Star, and several other humans are taken prisoner.